The JPB Foundation, headquartered at 875 Third Avenue, 29th Floor, New York, NY 10022, is a philanthropic organization dedicated to creating significant and lasting change in the United States. The foundation focuses on three main areas: alleviating poverty, sustaining and enriching the environment, and advancing pioneering medical research. By supporting initiatives that aim to create long-term, impactful changes, JPB Foundation seeks to empower those living in poverty, promote health equity, and foster economic justice.

The foundation operates through a collaborative grantmaking model, meaning it works closely with selected organizations to fund projects that align with its mission. JPB Foundation does not accept unsolicited proposals; instead, it carefully selects and invites organizations to apply for grants. This selective approach ensures that the foundation partners with visionary leaders and strong organizations capable of driving substantial and enduring change.

JPB Foundation's business model revolves around providing financial support to U.S.-based grantees. It does not engage in advocacy or attempts to influence legislation. Instead, it focuses on funding initiatives that can prevent issues rather than merely addressing them after they arise. This proactive approach is evident in its support for medical research, particularly in the areas of chronic diseases and neurological dysfunction, where it funds world-class scientists to explore innovative solutions.

The foundation's clients are primarily non-profit organizations and research institutions in the United States that align with its mission. By fostering productive partnerships and promoting diversity, equity, and inclusion, JPB Foundation aims to amplify its impact far beyond what it could achieve alone.

In summary, JPB Foundation is a philanthropic organization that empowers those in poverty, supports environmental sustainability, and advances medical research through selective and strategic grantmaking.

Keywords: philanthropy, poverty alleviation, environmental sustainability, medical research, grantmaking, health equity, economic justice, collaborative partnerships, U.S.-based, proactive prevention.